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Search Results for " Protein kinase A "

ターゲット

CaMK Casein Kinase PKA PKC

496

阻害剤

天然化合物

970

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T14069	A-3 hydrochloride		CaMK , Casein Kinase , PKA , PKC
	A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectiv...		CaMK , Casein Kinase , PKA , PKC
T7648	HA-100		Myosin , PKA , PKC
	HA-100 is an inhibitor of protein kinase		Myosin , PKA , PKC
T14072	A-443654		ERK , VEGFR , GSK-3 , FLT , Casein Kinase , MAPK , Akt , PKA , Chk , CDK , Src , PKC , S6 Kinase
	A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).
T2468	A-769662	A 769662	AMPK , Fatty Acid Synthase
	A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).		AMPK , Fatty Acid Synthase
T6139	A-674563	A674563	ERK , GSK-3 , Akt , PKA , CDK
	A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.		ERK , GSK-3 , Akt , PKA , CDK
T2482	AT13148		ROCK , SGK , Akt , PKA , S6 Kinase
	AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.		ROCK , SGK , Akt , PKA , S6 Kinase
T6304	AT7867		Akt , PKA , S6 Kinase
	AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family.		Akt , PKA , S6 Kinase
T3498	CCG215022		GRK , PKA
	CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, 5 and 1, respectively.		GRK , PKA
T6250	H-89 dihydrochloride	Protein kinase inhibitor H-89 dihydrochloride,H 89 2HCl,5-Isoquinolinesulfonamide	PKA , S6 Kinase , Autophagy
	H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).		PKA , S6 Kinase , Autophagy
T7659	Bisindolylmaleimide IV		Others , PKC
	Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)		Others , PKC
T1606	Fasudil	HA-1077,AT877	ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy
	Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T3586	Compound 401	2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one	DNA-PK
	Compound 401 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one) is a synthetic DNA-PK inhibitor (IC50 = 0.28 μM) that also targets mTOR but not PI3K.		DNA-PK
T3269	Metadoxine	pyridoxine-pyrrolidone carboxylat,Metasin,Metadoxil	5-HT Receptor , PKA
	Metadoxine (Metadoxil) is a neurotransmitter stimulant.		5-HT Receptor , PKA
T3060	Fasudil hydrochloride	Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877	ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy
	Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T83728	Tat-AKAP79 (326-336) TFA	Tat-A-kinase Anchor Protein 79 (326-336)
	Tat-AKAP79 (326-336) is a peptide that links the HIV-1 Tat protein transduction domain with an 11-amino acid sequence from A-kinase anchor protein 79 (AKAP79). This compound effectively inhibits the activation-induced se...
TP1351	Kemptide		PKA
	Kemptide is a synthetic heptapeptide, acting as a substrate for cAMP-dependent protein kinase (PK).		PKA
T2287	PIK-75 hydrochloride	PIK-75 HCl,PIK-75	Apoptosis , DNA-PK , PI3K
	PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.		Apoptosis , DNA-PK , PI3K
T6747	8-Bromo-cAMP sodium salt	8-Br-Camp sodium salt,8-Bromo-cAMP(sodium salt),8-Bromo-cAMP	PKA
	8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. It is an activator of cyclic AMP-dependent protein kinase（PKA）, but resistant to degradation by cyclic AMP phosphodiesterase.		PKA
T1418	Bucladesine sodium	dbcAMP,Dibutyryl-cAMP sodium salt,Dibutyryl-cAMP,DC2797,Sodium dibutyryl cAMP,Bucladesine,Bucladesine sodium salt	PKA , PDE
	Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties. Bucladesine sodium is also a cAMP-dependent protein kinase (PKA) activator and a phosphodiester (PDE) inhibitor. Bucladesine sodium has anti-in...		PKA , PDE
T6146	Dorsomorphin dihydrochloride	BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride	AMPK , Autophagy , TGF-beta/Smad
	Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.		AMPK , Autophagy , TGF-beta/Smad
T9779	Protein kinase inhibitor 6
	Protein kinase inhibitor 6 is a protein kinase inhibitor.
T60109	Protein kinase inhibitor H-7	5-(2-methylpiperazine-1-sulfonyl)isoquinoline,1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine	PKC
	Protein kinase inhibitor H-7 (5-(2-methylpiperazine-1-sulfonyl)isoquinoline) is a potent inhibitor of protein kinase C (PKC) with a Ki of 6 μM. Protein kinase inhibitor H-7 is also a cyclic nucleotide dependent protein k...		PKC
T67755	Protein kinase G inhibitor-1		PKA
	Protein kinase G inhibitor-1 is a potent Protein kinase G inhibitor, IC50= 0.9 uM.		PKA
T4692	Protein kinase inhibitors 1 hydrochlorid	Protein kinase inhibitors 1 hydrochlorid (1365986-44-2(free base))	Others
	Protein kinase inhibitors 1 hydrochlorid (Protein kinase inhibitors 1 hydrochlorid (1365986-44-2(free base))) is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.		Others
T77628	Bisindolylmaleimide III		PKC
	Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6 protein kinase 1 upon activation of these kinases.		PKC
T21761	HNMPA		IGF-1R
	HNMPA is a membrane impermeable inhibitor of insulin receptor tyrosine kinase. HNMPA inhibits tyrosine and serine autophosphorylation by the human insulin receptor. HNMPA exhibits no effect on cyclic AMP-dependent prote...		IGF-1R
T22831	Protein kinase inhibitor H-7 dihydrochloride	H-7 dihydrochloride	PKC
	Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor. Protein kinase inhibitor H-7 dihydrochloride (100 μM) significantly inhibits TPA (skin tumor promoter, 12-O-...		PKC
TP1053L	Protein Kinase C 19-31 acetate	Protein Kinase C 19-31 acetate(121545-65-1 free base),PKC (19-31) acetate	PKC
	Protein Kinase C 19-31 acetate, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is...		PKC
T4442	MK2-IN-1 hydrochloride	MK2 Inhibitor,MK 25	MAPK
	MK2-IN-1 hydrochloride (MK 25) is a highly selective, non-ATP competitive inhibitor of p38/mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2 or MK2, IC50: 0.11 μM) [1].		MAPK
T9631	IRAK-4 protein kinase inhibitor 2		IRAK
	IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).		IRAK
T1858	CID-797718	CID 797718	Serine/threonin kinase
	CID-797718 is a protein kinase D1 (PKD1) inhibitor.		Serine/threonin kinase
T9034	MK2-IN-3	MK2 Inhibitor III	MAPK
	MK2-IN-3 (MK2 Inhibitor III) is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis		MAPK
T6815	HS-1371		RIP kinase
	HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.		RIP kinase
T3689	Ruboxistaurin hydrochloride	Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride	PKC
	Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCβI and PKCβII (IC50 values are 4.7 and 5.9 nM respectively). Sel...		PKC
T5508	PF-AKT400	AKT protein kinase inhibitor	Akt
	PF-AKT400 (AKT protein kinase inhibitor) is a broadly selective and ATP-competitive inhibitor of Akt.		Akt
T19836	2-Aminopurine		DNA/RNA Synthesis , PKA
	2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor.		DNA/RNA Synthesis , PKA
TP1787L	PKG Substrate acetate（81187-14-6 free base)		PKA
	PKG Substrate acetate is a selective substrate for cGMP-dependent protein kinase (PKG).PKG Substrate is a selective substrate for protein kinase G (PKG) with a strong preference for PKG Iα (Km = 59 μM) over PKG II (Km = ...		PKA
T8823	Locostatin		Raf
	Locostatin is a potent and cell permeable inhibitor of Raf kinase inhibitor protein (RKIP)/Raf1 kinase interaction and an inhibitor of cell migration.		Raf
T13807	OSIP-486823	CP248	Microtubule Associated , PKA
	OSIP-486823（CP248） is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.		Microtubule Associated , PKA
T74643	RSS0680		CDK , AMPK , AAK1 (AP2 associated kinase 1) , PROTACs
	RSS0680 is a protein kinase degrader that degrades a variety of kinases and can be used to study diseases caused by kinase abnormalities.		CDK , AMPK , AAK1 (AP2 associated kinase 1) , PROTACs
T60067	WAY-297174		Casein Kinase
	WAY-297174 is a human protein kinase CK2 inhibitor with IC50 of > 33 μM.		Casein Kinase
T11184	EML4-ALK kinase inhibitor 1	EML4 ALK kinase inhibitor 1,EML4-ALK kinase inhibitor 1	ALK
	EML4-ALK kinase inhibitor 1 (EML4 ALK kinase inhibitor 1) is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.		ALK
T9702	Eclitasertib		RIP kinase
	Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of <1 µΜ).		RIP kinase
T6130	Skepinone-L	CBS3830	p38 MAPK , Autophagy
	Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.		p38 MAPK , Autophagy
T3623	Cobimetinib	RG7420,XL518,GDC-0973	Apoptosis , MEK
	Cobimetinib (GDC-0973) is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). Cobimetinib specifically binds to and inhibits the catalytic activity of MEK1, resulting in inhibition of e...		Apoptosis , MEK
T9557	TNIK-IN-2		Wnt/beta-catenin
	TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.		Wnt/beta-catenin
T11501	GSK840	GSK'840	RIP kinase
			RIP kinase
T23589	9-Isopropylolomoucine	9 Isopropylolomoucine,N9 Isopropylolomoucine,N9Isopropylolomoucine,N9-Isopropylolomoucine	CDK
	9-Isopropylolomoucine (N9-Isopropylolomoucine), a cell cycle protein-dependent kinase inhibitor, is a thiopurine.		CDK
T15780	LP-922761		AAK1 (AP2 associated kinase 1)
	LP-922761 is a potent, selective, and orally active AAK1 inhibitor with inhibitory effects on BMP-2 induced protein kinase (BIKE).		AAK1 (AP2 associated kinase 1)
TQ0031	Nedisertib	M3814	DNA-PK
	Nedisertib (M3814) (M3814) is a specific inhibitor of DNA-dependent Protein Kinase (DNA-PK, IC50: <3 nM).		DNA-PK

Compounds

A-3 hydrochloride

T14069

Synonym:

Target: CaMK, Casein Kinase, PKA, PKC

HA-100

T7648

Synonym:

Target: Myosin, PKA, PKC

A-443654

T14072

Synonym:

Target: ERK, VEGFR, GSK-3, FLT, Casein Kinase, MAPK, Akt, PKA, Chk, CDK, Src, PKC, S6 Kinase

A-769662

T2468

Synonym: A 769662

Target: AMPK, Fatty Acid Synthase

A-674563

T6139

Synonym: A674563

Target: ERK, GSK-3, Akt, PKA, CDK

AT13148

T2482

Synonym:

Target: ROCK, SGK, Akt, PKA, S6 Kinase

AT7867

T6304

Synonym:

Target: Akt, PKA, S6 Kinase

Synonym: Protein kinase inhibitor H-89 dihydrochloride,H 89 2HCl,5-Isoquinolinesulfonamide

Target: PKA, S6 Kinase, Autophagy

Bisindolylmaleimide IV

Synonym: HA-1077,AT877

Target: ROCK, Serine/threonin kinase, Calcium Channel, PKA, PKC, Autophagy

Compound 401

T3586

Synonym: 2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one

Target: DNA-PK

Metadoxine

T3269

Synonym: pyridoxine-pyrrolidone carboxylat,Metasin,Metadoxil

Target: 5-HT Receptor, PKA

Fasudil hydrochloride

T3060

Synonym: Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877

Target: ROCK, Serine/threonin kinase, Calcium Channel, HIV Protease, PKA, PKC, Autophagy

Tat-AKAP79 (326-336) TFA

T83728

Synonym: Tat-A-kinase Anchor Protein 79 (326-336)

Synonym: PIK-75 HCl,PIK-75

Target: Apoptosis, DNA-PK, PI3K

8-Bromo-cAMP sodium salt

T6747

Synonym: 8-Br-Camp sodium salt,8-Bromo-cAMP(sodium salt),8-Bromo-cAMP

Target: PKA

Bucladesine sodium

T1418

Synonym: dbcAMP,Dibutyryl-cAMP sodium salt,Dibutyryl-cAMP,DC2797,Sodium dibutyryl cAMP,Bucladesine,Bucladesine sodium salt

Target: PKA, PDE

Dorsomorphin dihydrochloride

T6146

Synonym: BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride

Target: AMPK, Autophagy, TGF-beta/Smad

Protein kinase inhibitor 6

T9779

Synonym:

Target:

Protein kinase inhibitor H-7

T60109

Synonym: 5-(2-methylpiperazine-1-sulfonyl)isoquinoline,1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine

Target: PKC

Protein kinase G inhibitor-1

T67755

Synonym:

Target: PKA

Protein kinase inhibitors 1 hydrochlorid

T4692

Synonym: Protein kinase inhibitors 1 hydrochlorid (1365986-44-2(free base))

Target: Others

Bisindolylmaleimide III

Protein kinase inhibitor H-7 dihydrochloride

T22831

Synonym: H-7 dihydrochloride

Target: PKC

Protein Kinase C 19-31 acetate

TP1053L

Synonym: Protein Kinase C 19-31 acetate(121545-65-1 free base),PKC (19-31) acetate

Target: PKC

MK2-IN-1 hydrochloride

T4442

Synonym: MK2 Inhibitor,MK 25

Target: MAPK

IRAK-4 protein kinase inhibitor 2

Target: Serine/threonin kinase

MK2-IN-3

T9034

Synonym: MK2 Inhibitor III

Ruboxistaurin hydrochloride

T3689

Synonym: Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride

Target: PKC

PF-AKT400

T5508

Synonym: AKT protein kinase inhibitor

Target: DNA/RNA Synthesis, PKA

PKG Substrate acetate（81187-14-6 free base)

Target: Microtubule Associated, PKA

RSS0680

T74643

Synonym:

Target: CDK, AMPK, AAK1 (AP2 associated kinase 1), PROTACs

WAY-297174

T60067

Synonym:

Target: Casein Kinase

EML4-ALK kinase inhibitor 1

T11184

Synonym: EML4 ALK kinase inhibitor 1,EML4-ALK kinase inhibitor 1

Target: p38 MAPK, Autophagy

Cobimetinib

T3623

Synonym: RG7420,XL518,GDC-0973

Target: Apoptosis, MEK

TNIK-IN-2

T9557

Synonym:

Target: Wnt/beta-catenin

9-Isopropylolomoucine

T23589

Synonym: 9 Isopropylolomoucine,N9 Isopropylolomoucine,N9Isopropylolomoucine,N9-Isopropylolomoucine

Target: AAK1 (AP2 associated kinase 1)

カタログ番号	製品名	別名	ターゲット
T5771	Hypocrellin A		Antibacterial , PKC , Parasite
	Hypocrellin A is PKC inhibitor, has light-induced antitumor,antifungal and antiviral activities, it also exerts immunomodulatory effects on MHC-restricted presentation of antigen.		Antibacterial , PKC , Parasite
T5S0896	Loureirin A		Akt , PI3K
	Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related pept...		Akt , PI3K
T2851	Daphnetin	7,8-Dihydroxycoumarin,Daphnetol	EGFR , PKA , PKC , Parasite , Autophagy
	Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...		EGFR , PKA , PKC , Parasite , Autophagy
T4S0498	Glaucocalyxin A	Wangzaozin B,Leukamenin F	Apoptosis , Akt , Caspase , PI3K
	1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...		Apoptosis , Akt , Caspase , PI3K
T4S2128	Bilobetin		PKA , PPAR
	Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.		PKA , PPAR
TN1136	Procyanidin A1	Proanthocyanidin A1	LDL , Calcium Channel , PKC
	Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+; influx from an internal store in RBL-2H3 cells.		LDL , Calcium Channel , PKC
T2790	Oridonin	NSC-250682,Rubescenin,Isodonol,Rubescensin A	Akt , Antibacterial
	Oridonin (NSC-250682) is a diterpenoid isolated from Rabdosia rubescens with anti-tumor, anti-bacterial and anti-inflammatory effects. It acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2.		Akt , Antibacterial
T2P2806	Hederacolchiside A1	Raddeanoside R13	Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
	Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacol...		Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
TN1499	Cimiracemoside C	Cimicifugoside M	AMPK
	Cimiracemoside C (Cimicifugoside M) is an active component of Cimicifuga racemosa. It activates AMPK and has the potential activity against diabetes.		AMPK
T6680	Staurosporine	Antibiotic AM-2282,AM-2282,CGP 41251	Apoptosis , PKA , Antibacterial , Antibiotic , Src , PKC , Antifungal
	Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces...
T3P2904	α-Linolenic acid	Alpha-Linolenic Acid,Linolenic acid	Akt , PI3K
	α-Linolenic acid (Alpha-Linolenic Acid) is an essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been reported to inhibit the synthesis of prostagland...		Akt , PI3K
TN1033	Sennidin A		HCV Protease , transporter , Akt , PI3K
	Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 μM.		HCV Protease , transporter , Akt , PI3K
TN1694	Gliotoxin		Apoptosis , NF-κB , Wnt/beta-catenin , COX , PKA , Antibacterial , Antifection
	Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signaling pathway.
T7444	6-(Dimethylamino)purine	N,N-Dimethyladenine	Serine/threonin kinase , CDK
	6-(Dimethylamino)purine (N,N-Dimethyladenine) is a serine threonine protein kinase and CDK inhibitor		Serine/threonin kinase , CDK
T4037	Phorbol	4β-Phorbol,(+)-Phorbol	PKC
	Phorbol (4β-Phorbol), a plant-derived diterpene, is a tumor promoter through the activation of protein kinase C.		PKC
T3375	Verbascoside	Kusaginin,Acteoside,TJC160	Apoptosis , PARP , Antibacterial , PKC , p53 , HSV
	Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.		Apoptosis , PARP , Antibacterial , PKC , p53 , HSV
T5891	D-ERYTHRO-SPHINGOSINE	trans-4-Sphingenine,erythro-C18-Sphingosine,Erythrosphingosine	Phosphatase , Endogenous Metabolite , PKC
	D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator		Phosphatase , Endogenous Metabolite , PKC
TN1096	Ginsenoside Ra1		Others , Tyrosine Kinases
	Ginsenoside Ra1 is a component from ginseng. Ginsenoside Ra1 shows significant inhibitory effects on protein tyrosine kinase (PTK) activation induced by hypoxia/reoxygenation (H/R).		Others , Tyrosine Kinases
T9605	Sangivamycin	BA-90912,NSC 65346	Nucleoside Antimetabolite/Analog , PKC
	Sangivamycin (NSC-65346) is an effective inhibitor of protein kinase C (PKC, Ki = 10 μM). Sangivamycin exhibits antiproliferative activity against a variety of human cancers.		Nucleoside Antimetabolite/Analog , PKC
T3419	Chelerythrine chloride		Apoptosis , BCL , PKC , Autophagy
	Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to ATP.		Apoptosis , BCL , PKC , Autophagy
T5239	Cholesteryl sulfate sodium	Cholesterol 3-Sulfate Sodium Salt,Sodium Cholesteryl Sulfate	Endogenous Metabolite , PKC
	Cholesteryl sulfate sodium (Sodium Cholesteryl Sulfate) is a sterol sulfate in human plasma. Cholesteryl sulfate sodium is a component of cell membrane and has a regulatory function. Cholesteryl sulfate sodium also activ...		Endogenous Metabolite , PKC
TN1448	(-)-Bornyl acetate	L-(-)-Bornyl acetate,Bornyl acetate	p38 MAPK , NF-κB , JNK , Antifungal
	(-)-Bornyl acetate (L-(-)-Bornyl acetate) is a less active enantiomer of (+)-Bornyl acetate. (-)-Bornyl acetate isolates from hyssop oil and possesses antifungal activity. (-)-Bornyl acetate shows highly active whitening...		p38 MAPK , NF-κB , JNK , Antifungal
T6427	Butein	2’,3,4,4’-tetrahydroxy Chalcone	Apoptosis , EGFR , Others , PDE , Autophagy
	Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.		Apoptosis , EGFR , Others , PDE , Autophagy
T6S0052	Chelerythrine	Toddalin,Broussonpapyrine,Cheleritrine	Apoptosis , BCL , PKC , Autophagy
	1. Chelerythrine (Broussonpapyrine) may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has potential antiprolifera...		Apoptosis , BCL , PKC , Autophagy
T11665	Ionomycin calcium	SQ23377 calcium	Apoptosis , Calcium Channel , Antibacterial , Antibiotic , PKC

T4915	β-Glycerophosphate disodium salt hydrate		Phosphatase , Endogenous Metabolite
	β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It func...		Phosphatase , Endogenous Metabolite
T5S0581	Sec-O-Glucosylhamaudol	Hamaudol 3-glucoside	Others , Opioid Receptor
	Sec-O-Glucosylhamaudol (Hamaudol 3-glucoside) has anti-inflammatory effect through regulation of p38 Mitogen-Activated Protein Kinase in Lipopolysaccharide-stimulated RAW264.7 cell line. Intrathecal Sec-O-Glucosylhamaudo...		Others , Opioid Receptor
T3904	Gomisin J		Calcium Channel , AMPK
	Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK...		Calcium Channel , AMPK
T3877	Esculentoside A		NF-κB , COX
	Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. Esculentoside A may be useful for the treatment of autoimmun...		NF-κB , COX
T7285	Ionomycin		Calcium Channel
	Ionomycin is an calcium ionophore and an antibiotic that binds calcium ions (Ca2+). It is produced by the bacterium Streptomyces conglobatus.It is used in research to raise the intracellular calcium level (Ca2+) and as ...		Calcium Channel
T2S2043	Dracorhodin perchlorate	Dracorhodin perochlorate,Dracohodin perochlorate	Apoptosis , Others
	Dracorhodin perchlorate inhibits cell growth, and induces apoptosis in fibroblasts in a dose-and time-dependent manner, arresting cell cycle at G1 phase, may as a candidate for anti-breast cancer. Dracorhodin perchlorate...		Apoptosis , Others
T6S1597	Mulberroside A		TNF , Tyrosinase , Interleukin
	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...		TNF , Tyrosinase , Interleukin
T4S0800	Demethyleneberberine		P450 , NOS , NF-κB , HIF , AMPK
	Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.Demethyleneberberine suppresses CYP2E1,...		P450 , NOS , NF-κB , HIF , AMPK
T6S1418	Praeruptorin C		Antioxidant , Calcium Channel
	1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ...		Antioxidant , Calcium Channel
T5065	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD	Monosodium-GMP,cGMP sodium salt,Cyclic GMP	PKA
	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) , also known as cGMP, is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, inc...		PKA
T6S1369	Vitexin	Apigenin-8-C-glucoside	Antioxidant
	1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit...		Antioxidant
T6429	Caffeic Acid Phenethyl Ester	Phenylethyl Caffeate,CAPE	Apoptosis , NF-κB
	Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective...		Apoptosis , NF-κB
T5S0754	Isoquercetin	3-Glucosylquercetin,Hirsutrin,Isoquercitrin,Quercetin 3-o-glucopyranoside	NF-κB , Wnt/beta-catenin , NO Synthase
	1. Isoquercetin (3-Glucosylquercetin) is a potential stimulator of bone mineralization used for prophylaxis of osteoporotic disorders. 2. Isoquercetin may be as a potential therapeutic agent against neurodegeneration in ...		NF-κB , Wnt/beta-catenin , NO Synthase
T6S1684	8-Gingerol		Antioxidant , Antibacterial , TRP/TRPV Channel
	1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristic...		Antioxidant , Antibacterial , TRP/TRPV Channel
T1719	Bufalin		ATPase
	Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potenti...		ATPase
T3929	Kaurenoic acid	Kauren-19-Oic Acid,kaurenoate,kaur-16-en-18-oic acid	Others
	Kaurenoic acid (kaurenoate) has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level. Kaurenoic acid exerts a uterine relaxant effect acting principally through calcium blockade and in part,...		Others
T23772	Balanol	Ophiocordin,BA1,Azepinostatin,(-)-Balanol,(3R-trans)-Balanol
	Balanol is an ATP-competitive Protein Kinase C and Protein Kinase A inhibitor.
T22723	Dihydrosphingosine		Others
	Dihydrosphingosine is a Protein kinase C inhibitor.		Others
T17198	UCN-02	7-epi-Hydroxystaurosporine	Others
	UCN-02 is a selective protein kinase C inhibitor produced by Streptomyces strain N-12 (IC50s: 62 nM and 250 nM for PKC and protein kinase A (PKA), respectively).		Others
T15636	K-252a	Antibiotic K 252a,Antibiotic SF 2370,SF2370	Others
	K-252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi. K-252a inhibits protein kinase (IC50: 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphoryla...		Others
TN3711	Corylifol C		ERK , EGFR , p38 MAPK , MEK
	Corylifol C and, to a lesser extent, xanthoangelol are potent protein kinase inhibitors (inhibitory concentration 50% values for epidermal growth factor receptor (EGFR): 1.1 and 4.4 × 10(-6) μg/ml, respectively).		ERK , EGFR , p38 MAPK , MEK
T75565	Vanicoside A
	Vanicoside A is a protein kinase C( PKC ) inhibitor from Polygonum pensylvanicum [1] .
T16726	Rebeccamycin		Topoisomerase
	Rebeccamycin is an antitumor antibiotic+ inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I. It also has a negligible effect on protein kinase C and...		Topoisomerase
T21441	Prostratin	12-Deoxyphorbol-13-acetate
	Prostratin, a protein kinase C activator, has been shown to exhibit promising therapeutic potential against other diseases such as cancer and Alzheimer's disease. Prostratin has the potential to be useful in the treatmen...
T15637	K-252b		PKC
	K-252b, an indolocarbazole derived from the actinomycete Nocardiopsis, functions as a protein kinase C (PKC) inhibitor. It is effective in inhibiting extracellular kinases in cultured cells due to its inability to freely...		PKC
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天然物製品

Hypocrellin A

T5771

Synonym:

Target: Antibacterial, PKC, Parasite

Synonym: 7,8-Dihydroxycoumarin,Daphnetol

Target: EGFR, PKA, PKC, Parasite, Autophagy

Glaucocalyxin A

T4S0498

Synonym: Wangzaozin B,Leukamenin F

Target: Apoptosis, Akt, Caspase, PI3K

Synonym: Proanthocyanidin A1

Target: LDL, Calcium Channel, PKC

Oridonin

T2790

Synonym: NSC-250682,Rubescenin,Isodonol,Rubescensin A

Target: Akt, Antibacterial

Hederacolchiside A1

T2P2806

Synonym: Raddeanoside R13

Target: Apoptosis, ERK, MEK, Akt, PI3K, Parasite, mTOR

Cimiracemoside C

TN1499

Synonym: Cimicifugoside M

Target: AMPK

Staurosporine

T6680

Synonym: Antibiotic AM-2282,AM-2282,CGP 41251

Target: Apoptosis, PKA, Antibacterial, Antibiotic, Src, PKC, Antifungal

α-Linolenic acid

T3P2904

Synonym: Alpha-Linolenic Acid,Linolenic acid

Target: HCV Protease, transporter, Akt, PI3K

Gliotoxin

TN1694

Synonym:

Target: Apoptosis, NF-κB, Wnt/beta-catenin, COX, PKA, Antibacterial, Antifection

6-(Dimethylamino)purine

T7444

Synonym: N,N-Dimethyladenine

Target: Serine/threonin kinase, CDK

Phorbol

T4037

Synonym: 4β-Phorbol,(+)-Phorbol

Target: PKC

Verbascoside

T3375

Synonym: Kusaginin,Acteoside,TJC160

Target: Apoptosis, PARP, Antibacterial, PKC, p53, HSV

D-ERYTHRO-SPHINGOSINE

T5891

Synonym: trans-4-Sphingenine,erythro-C18-Sphingosine,Erythrosphingosine

Target: Phosphatase, Endogenous Metabolite, PKC

Ginsenoside Ra1

TN1096

Synonym:

Target: Others, Tyrosine Kinases

Sangivamycin

T9605

Synonym: BA-90912,NSC 65346

Target: Nucleoside Antimetabolite/Analog, PKC

Chelerythrine chloride

T3419

Synonym:

Target: Apoptosis, BCL, PKC, Autophagy

Cholesteryl sulfate sodium

T5239

Synonym: Cholesterol 3-Sulfate Sodium Salt,Sodium Cholesteryl Sulfate

Target: Endogenous Metabolite, PKC

(-)-Bornyl acetate

TN1448

Synonym: L-(-)-Bornyl acetate,Bornyl acetate

Target: p38 MAPK, NF-κB, JNK, Antifungal

Butein

T6427

Synonym: 2’,3,4,4’-tetrahydroxy Chalcone

Target: Apoptosis, EGFR, Others, PDE, Autophagy

Chelerythrine

T6S0052

Synonym: Toddalin,Broussonpapyrine,Cheleritrine

Target: Apoptosis, BCL, PKC, Autophagy

Ionomycin calcium

T11665

Synonym: SQ23377 calcium

Target: Apoptosis, Calcium Channel, Antibacterial, Antibiotic, PKC

β-Glycerophosphate disodium salt hydrate

T4915

Synonym:

Target: Phosphatase, Endogenous Metabolite

Sec-O-Glucosylhamaudol

T5S0581

Synonym: Hamaudol 3-glucoside

Target: Others, Opioid Receptor

Gomisin J

T3904

Synonym:

Target: Calcium Channel, AMPK

Target: Calcium Channel

Dracorhodin perchlorate

T2S2043

Synonym: Dracorhodin perochlorate,Dracohodin perochlorate

Target: Apoptosis, Others

Mulberroside A

T6S1597

Synonym:

Target: TNF, Tyrosinase, Interleukin

Demethyleneberberine

T4S0800

Synonym:

Target: P450, NOS, NF-κB, HIF, AMPK

Praeruptorin C

T6S1418

Synonym:

Target: Antioxidant, Calcium Channel

GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD

T5065

Synonym: Monosodium-GMP,cGMP sodium salt,Cyclic GMP

Target: PKA

Vitexin

T6S1369

Synonym: Apigenin-8-C-glucoside

Target: Antioxidant

Caffeic Acid Phenethyl Ester

T6429

Synonym: Phenylethyl Caffeate,CAPE

Target: Apoptosis, NF-κB

Isoquercetin

T5S0754

Synonym: 3-Glucosylquercetin,Hirsutrin,Isoquercitrin,Quercetin 3-o-glucopyranoside

Target: NF-κB, Wnt/beta-catenin, NO Synthase

8-Gingerol

T6S1684

Synonym:

Target: Antioxidant, Antibacterial, TRP/TRPV Channel

Synonym: Kauren-19-Oic Acid,kaurenoate,kaur-16-en-18-oic acid

Target: Others

Balanol

T23772

Synonym: Ophiocordin,BA1,Azepinostatin,(-)-Balanol,(3R-trans)-Balanol

Synonym: 7-epi-Hydroxystaurosporine

Target: Others

K-252a

T15636

Synonym: Antibiotic K 252a,Antibiotic SF 2370,SF2370

Target: ERK, EGFR, p38 MAPK, MEK

Target: Topoisomerase

Prostratin

T21441

Synonym: 12-Deoxyphorbol-13-acetate

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00405	EphA4 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Ephrin type-A receptor 4(EPHA4) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHA4 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. EPH and ...
TMPJ-00404	EphA4 Protein, Human, Recombinant	Human	Human Cells
	Ephrin type-A receptor 4(EPHA4) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHA4 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. EPH and ...
TMPJ-00304	ALK-1 Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10. ALK1 signaling is necessary for angi...
TMPJ-01382	HSPB8 Protein, Human, Recombinant (His)	Human	E. coli
	Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in t...
TMPJ-00242	PARVA Protein, Human, Recombinant (His)	Human	E. coli
	Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with i...
TMPJ-00546	EFNA1 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can ...
TMPY-04572	MKK4 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is...
TMPY-00637	FLT1 Protein, Human, Recombinant (aa 1-328, His)	Human	HEK293
	Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPY-04384	Src Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C...
TMPJ-00412	VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ...
TMPY-04750	CSNK2A2 Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	Casein kinase II subunit alpha', also known as CSNK2A2 and CK2A2, is a member of the protein kinase superfamily, Ser/Thr protein kinase family and CK2 subfamily. Casein kinases are operationally defined by their prefer...
TMPY-05655	C-Kit Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-04051	C-Kit Protein, Human, Recombinant (hFc)	Human	HEK293
	C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-01935	C-Kit Protein, Human, Recombinant (His)	Human	HEK293
	C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-01802	C-Kit Protein, Mouse, Recombinant (His)	Mouse	HEK293
	C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-02028	RON/CD136 Protein, Human, Recombinant (His)	Human	HEK293
	The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. ...
TMPJ-00335	TGFBR2 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinit...
TMPY-04483	IRAK4 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPY-05157	TGFBR2 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPY-04376	PLK1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Serine / threonine-protein kinase PLK1 / PLK-1, also known as polo-like kinase 1 (PLK-1) or serine / threonine-protein kinase 13 (STPK13), Polo-like kinases (PLKs), is a family of four serine / threonine protein kinases ...
TMPY-00882	Mer Protein, Human, Recombinant (His & hFc)	Human	HEK293
	Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-04330	Mer Protein, Human, Recombinant	Human	HEK293
	Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-04548	CDK4 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	CDK4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cel...
TMPY-03848	Protein S/PROS1 Protein, Human, Recombinant (His)	Human	HEK293
	PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free,...
TMPY-04552	AKT1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to ...
TMPY-01786	EphB4 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephr...
TMPY-00756	FGF-1 Protein, Human, Recombinant	Human	E. coli
	aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which re...
TMPY-02361	VEGFR2/KDR Protein, Human, Recombinant (His)	Human	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-01146	Insulin Receptor Protein, Human, Recombinant (long isoform, His)	Human	HEK293
	INSR (Insulin receptor), also known as CD22, is a transmembrane receptor that is activated by insulin. INSR belongs to the protein kinase superfamily and exists as a tetramer consisting of two alpha subunits and two beta...
TMPY-01560	EGF Protein, Human, Recombinant	Human	E. coli
	EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats. ...
TMPY-01062	EGF Protein, Human, Recombinant (hFc)	Human	HEK293
	EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats. ...
TMPY-00341	FGFR3 Protein, Human, Recombinant (alpha IIIb, His)	Human	HEK293
	FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPY-02953	TEM8/ANTXR1 Protein, Human, Recombinant (hFc)	Human	HEK293
	ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are ser...
TMPY-06984	EGF Protein, Mouse, Recombinant (Yeast)	Mouse	Yeast
	EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats. ...
TMPY-01053	Prolactin Receptor Protein, Human, Recombinant (His)	Human	HEK293
	Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type I cytokine receptor superfamily, and contains two fibronectin type-III domains. All class 1 ligands activate their respective recept...
TMPY-05592	ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated	Human	HEK293
	NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e...
TMPY-04165	FGFR3 Protein, Human, Recombinant (His)	Human	HEK293
	FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPJ-00375	HGF Protein, Human, Recombinant (His)	Human	Human Cells
	HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propepti...
TMPY-01296	HGFR/c-Met Protein, Human, Recombinant (His)	Human	HEK293
	Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR...
TMPY-00548	HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR...
TMPY-02112	FGFR4 Protein, Human, Recombinant (His)	Human	HEK293
	Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibroblast growth factor receptor family, where amino acid seque...
TMPY-01896	HGFR/c-Met Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR...
TMPY-02333	ULBP-2 Protein, Human, Recombinant (His)	Human	HEK293
	NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e...
TMPY-04125	PTP1B Protein, Human, Recombinant (His)	Human	E. coli
	PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c...
TMPY-00399	HER3/ERBB3 Protein, Human, Recombinant	Human	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-02477	HER3/ERBB3 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-02365	HER3/ERBB3 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-04774	ALK-2/ACVR1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-01389	HER3/ERBB3 Protein, Human, Recombinant (His)	Human	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-00246	HER3/ERBB3 Protein, Rhesus, Recombinant	Rhesus	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
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EphA4 Protein, Human, Recombinant (hFc)

TMPJ-00405

Species: Human

Expression System: Human Cells

EphA4 Protein, Human, Recombinant

TMPJ-00404

Species: Human

Expression System: Human Cells

ALK-1 Protein, Mouse, Recombinant (hFc)

TMPJ-00304

Species: Mouse

Expression System: Human Cells

HSPB8 Protein, Human, Recombinant (His)

TMPJ-01382

Species: Human

Expression System: E. coli

PARVA Protein, Human, Recombinant (His)

TMPJ-00242

Species: Human

Expression System: E. coli

EFNA1 Protein, Human, Recombinant (hFc)

TMPJ-00546

Species: Human

Expression System: Human Cells

MKK4 Protein, Mouse, Recombinant (His & GST)

TMPY-04572

Species: Mouse

Expression System: Baculovirus-Insect Cells

FLT1 Protein, Human, Recombinant (aa 1-328, His)

TMPY-00637

Species: Human

Expression System: HEK293

Src Protein, Human, Recombinant (His & GST)

TMPY-04384

Species: Human

Expression System: Baculovirus-Insect Cells

VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

TMPJ-00412

Species: Human

Expression System: Human Cells

CSNK2A2 Protein, Human, Recombinant

TMPY-04750

Species: Human

Expression System: Baculovirus-Insect Cells

c-Kit Protein, Rhesus, Recombinant (hFc)

TMPY-05655

Species: Rhesus

Expression System: HEK293

c-Kit Protein, Human, Recombinant (hFc)

TMPY-04051

Species: Human

Expression System: HEK293

c-Kit Protein, Human, Recombinant (His)

TMPY-01935

Species: Human

Expression System: HEK293

c-Kit Protein, Mouse, Recombinant (His)

TMPY-01802

Species: Mouse

Expression System: HEK293

RON/CD136 Protein, Human, Recombinant (His)

TMPY-02028

Species: Human

Expression System: HEK293

TGFBR2 Protein, Mouse, Recombinant (His)

TMPJ-00335

Species: Mouse

Expression System: Human Cells

IRAK4 Protein, Human, Recombinant (His)

TMPY-04483

Species: Human

Expression System: Baculovirus-Insect Cells

TGFBR2 Protein, Human, Recombinant (His)

TMPY-05157

Species: Human

Expression System: Baculovirus-Insect Cells

PLK1 Protein, Human, Recombinant (His)

TMPY-04376

Species: Human

Expression System: Baculovirus-Insect Cells

Mer Protein, Human, Recombinant (His & hFc)

TMPY-00882

Species: Human

Expression System: HEK293

Mer Protein, Human, Recombinant

TMPY-04330

Species: Human

Expression System: HEK293

CDK4 Protein, Human, Recombinant (GST)

TMPY-04548

Species: Human

Expression System: Baculovirus-Insect Cells

Protein S/PROS1 Protein, Human, Recombinant (His)

TMPY-03848

Species: Human

Expression System: HEK293

AKT1 Protein, Human, Recombinant (His)

TMPY-04552

Species: Human

Expression System: Baculovirus-Insect Cells

EphB4 Protein, Mouse, Recombinant (hFc)

TMPY-01786

Species: Mouse

Expression System: HEK293

FGF-1 Protein, Human, Recombinant

TMPY-00756

Species: Human

Expression System: E. coli

VEGFR2/KDR Protein, Human, Recombinant (His)

TMPY-02361

Species: Human

Expression System: HEK293

Insulin Receptor Protein, Human, Recombinant (long isoform, His)

TMPY-01146

Species: Human

Expression System: HEK293

EGF Protein, Human, Recombinant

TMPY-01560

Species: Human

Expression System: E. coli

EGF Protein, Human, Recombinant (hFc)

TMPY-01062

Species: Human

Expression System: HEK293

FGFR3 Protein, Human, Recombinant (alpha IIIb, His)

TMPY-00341

Species: Human

Expression System: HEK293

TEM8/ANTXR1 Protein, Human, Recombinant (hFc)

TMPY-02953

Species: Human

Expression System: HEK293

EGF Protein, Mouse, Recombinant (Yeast)

TMPY-06984

Species: Mouse

Expression System: Yeast

Prolactin Receptor Protein, Human, Recombinant (His)

TMPY-01053

Species: Human

Expression System: HEK293

ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated

TMPY-05592

Species: Human

Expression System: HEK293

FGFR3 Protein, Human, Recombinant (His)

TMPY-04165

Species: Human

Expression System: HEK293

HGF Protein, Human, Recombinant (His)

TMPJ-00375

Species: Human

Expression System: Human Cells

HGFR/c-Met Protein, Human, Recombinant (His)

TMPY-01296

Species: Human

Expression System: HEK293

HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-00548

Species: Cynomolgus,Rhesus

Expression System: HEK293

FGFR4 Protein, Human, Recombinant (His)

TMPY-02112

Species: Human

Expression System: HEK293

HGFR/c-Met Protein, Mouse, Recombinant (His)

TMPY-01896

Species: Mouse

Expression System: HEK293

ULBP-2 Protein, Human, Recombinant (His)

TMPY-02333

Species: Human

Expression System: HEK293

PTP1B Protein, Human, Recombinant (His)

TMPY-04125

Species: Human

Expression System: E. coli

HER3/ERBB3 Protein, Human, Recombinant

TMPY-00399

Species: Human

Expression System: HEK293

HER3/ERBB3 Protein, Rhesus, Recombinant (His)

TMPY-02477

Species: Rhesus

Expression System: HEK293

HER3/ERBB3 Protein, Mouse, Recombinant (His)

TMPY-02365

Species: Mouse

Expression System: HEK293

ALK-2/ACVR1 Protein, Human, Recombinant (His)

TMPY-04774

Species: Human

Expression System: Baculovirus-Insect Cells

HER3/ERBB3 Protein, Human, Recombinant (His)

TMPY-01389

Species: Human

Expression System: HEK293

HER3/ERBB3 Protein, Rhesus, Recombinant

TMPY-00246

Species: Rhesus

Expression System: HEK293

--------- More ---------

カタログ番号	製品名
L1610	FDA-Approved Kinase Inhibitor Library	263 compounds
	A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
L2200	Tyrosine Kinase Inhibitor Library	1033 compounds
	A unique collection of 1033 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases;
L1600	Kinase Inhibitor Library	2700 compounds
	A unique collection of 2700 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;
L1120	AMPK-Targeted Compound Library	80 compounds
	80 well-chosen unique AMPK-targeted small molecules；
L1300	PI3K-AKT-mTOR Compound Library	420 compounds
	A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;
L7700	Neural Regeneration Compound Library	529 compounds
	A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening;
L1400	MAPK Inhibitor Library	365 compounds
	A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;
L3800	NF-κB Signaling Compound Library	740 compounds
	A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L9410	Covalent Inhibitor Library	1949 compounds
	A unique collection of 1949 covalent Inhibitors and other molecules with common warheads like chloroacetyl，2-Chloropropionyl，Acryloyl，sulfonyl fluoride, alkyne，acrylamide, ketocarbonyl，disulfide bond, etc.